New Frontiers of Sobriety

Newton’s third law of motion states that for every action there is an equal and opposite reaction. In particle physics we learn that for all matter there can be antimatter of opposite charge. But what about drugs? Is there an anti-weed, an anti-heroin, or an anti-beer? Pharmacologically speaking, the answer is yes. Scientists can identify regions of the brain stimulated by a given drug and then create an anti-drug with the opposite mechanism of action. Substances that do the opposite of common recreational drugs are useful in overdoses but rarely become recreational drugs in their own right for the simple reason that they make you feel totally and completely miserable. I decided to systematically test three of the most powerful anti-highs over the course of one week. Here are my results: Worst omelet ever. Thanks, rimonabant. Photo by Maggie Lee ANTI-WEED: RIMONABANT DOSE: 60 MG could I am the least high person in the universe. Photo by Maggie Lee ANTI-LSD: RISPERIDONE DOSE: 4 MG At the Chinatown needle exchange, where I am apparently a regular. Photo by Jess Williamson ANTI-HEROIN: NALTREXONE DOSE: 200 MG Ulysses Ulysses CONCLUSION