12:05pm ET:Farhad Khan, the brother-in-law of Syed Farook, just spoke briefly at a press conference hosted by the Council on American-Islamic Relations."I just cannot express at how sad I am for what happened today," he said. "I have no idea why he would do that, why he would do something like this."Khan is the husband of Farook's sister. He declined to offer any details about Farook or his family."The reason I'm here is to talk to the victims and to express for my family how sad we are about what happened," he said.Impromptu vigil forms near the scene of today's horrific #SanBernardino shootings. pic.twitter.com/hZl9EuAa6H
— Tom (T.J.) Wait (@CBSLATom) December 3, 2015
8:17pm ET:A spokesperson for the Loma Linda Medical Center says they have five adult patients from today's shootings. Two are in critical but stable condition, two are in fair condition, and one is still being assessed.Ca shooting: FBI stepping into leadership role in San Bernardino investigation after suspect(s) allegedly threw pipe bombs or IEDs from SUV
— Rick Serrano (@RickSerranoLAT)December 3, 2015
7:15pm ET:Police surrounded a house about a mile away from where the shootout with the SUV occurred and searched it with guns drawn. They now appear to be going door-to-door in the neighborhood, possibly in search of the third suspect.We are asking that all people in the SB area south of San Bernardino Ave east of Mt. View stay in their homes w/doors locked & secure
— SB County Sheriff (@sbcountysheriff)December 3, 2015
6:18pm ET:Television images show police surrounding a man laying on the ground with a large pool of blood nearby and what appears to be a rifle laying a few feet away. A black SUV with dozens of bullet holes is stopped near the man, with its window open.There is an active scene unfolding in San Bernardino. Preliminary info is a suspect is down, officers are ok. Not confirmed if related.
— SB County Sheriff (@sbcountysheriff)December 2, 2015
Horrifying news out of — Martin O'Malley (@MartinOMalley)December 2, 2015
4:25pm ET: Employees of the Inland Regional Center have been evacuated from the scene of the shooting in yellow buses.Loma Linda University Medical Center has confirmed it has received at least four people to its trauma center. Spokeswoman Briana Pastorino told the AP she did not know the condition of the patients and said the hospital was expecting at least three more people.4:14pm ET: Hillary Clinton has commented on the shooting:California shooting looks very bad. Good luck to law enforcement and God bless. This is when our police are so appreciated!
— Donald J. Trump (@realDonaldTrump)December 2, 2015
4:09pm ET:Police have confirmed "multiple casualties, including fatalities" in the shooting. Sgt. Vicki Cervantes of the San Bernardino Police Department said she could not confirm numbers at this time as the scene is still active. It's not clear if the gunmen, who may be one of possibly three, is still inside the building. Authorities have asked local media not to show the area where they are operating. TV images show police continuing to lead people out of the building, more than an hour after the first reports of the shooting emerged.3:55pm ET: The building where shooting has broken out at the center reportedly houses at least 25 employees as well as a library and conference center, Marybeth Feild The president and CEO of the Inland Regional Center, told the Associated Press. Field said the "incident is in the conference area," which is being rented by an unknown outside group.3:45pm ET: The White House says President Barack Obama has been briefed on the latest shooting in San Bernardino by his homeland security adviser, Lisa Monaco. Earlier on Tuesday, the president said Congress must act to ensure that people who are "deranged" or have "violent tendencies" cannot get their hands on weapons to inflict mass murder."We don't yet know what the motives of the shooters are but what we do know is that there are steps we can take to make Americans safer," Obama said in an interview with CBS News. "We should never think that this is just something that just happens in the ordinary course of events because it doesn't happen with the same frequency in other countries."I refuse to accept this as normal. We must take action to stop gun violence now. -H — Hillary Clinton (@HillaryClinton)December 2, 2015
The latest mass shooting come less than a week after a gunman opened fire at a Planned Parenthood clinic in Colorado Springs the day after the Thanksgiving holiday. One policeman and two civilians died in that shooting.3:41pm ET: The father of another witness, Terry Petit, says his daughter text him saying: "People shot. In the office waiting for cops. Pray for us. I am locked in an office."Petit read the text to reporters outside the Inland Regional Center in San Bernardino, where several law enforcement agencies are currently converged.On an average day, doctors at the regional center would be evaluating toddlers whose parents have concerns and case workers meeting with developmentally disabled adults. Nancy Lungren, spokeswoman for the California Department of Developmental Services said that the San Bernardino facility is one of the state's largest and busiest. The center currently serves about 30,000 clients a year.3:25pm ET: Television images show dozens of police and law enforcement vehicles parked outside the Inland Regional Center in San Bernardino.Marcos Aguilera told a local ABC affiliate that his wife was in the building when the shooter entered the office next to her and opened fire.Active Shooter: Possible 3 gunman, possible total 20 Victims with possible 12 deceased. Pray for San Bernadino! ???????? — ? KING SULLIVAN ? (@timsullivan23)December 2, 2015
3:07pm ET: The shooting in San Bernardino occurred at the Inland Regional Center, one of 21 facilities serving people with developmental disabilities run by the state, said Nancy Lungren, spokeswoman for the California Department of Developmental Services. The center is located in an office park surrounded by a parking lot, near a golf course. Television images showed people walking out of the facility with their hands up. Local TV news stations said police told them that there could possibly be one to three shooters still at large.A spokeswoman with the San Bernardino Sheriff's Office told VICE News it is assisting San Bernardino police at the scene. The SBPD said it received the first call at 10:59am of multiple shots fired.2:45pm ET: San Bernardino police say there are as many as three suspects involved in a shooting involving multiple victims.The San Bernardino Fire Department issued a tweet at 11:14am saying its units were dispatched to an incident involving 20 people at the 1300 block of S. Waterman.WATCH LIVE: Coverage of shooting in San Bernardino, California — NBC News (@NBCNews)December 2, 2015
The San Bernardino County Sheriff's Department told people to stay away from the area.SBFD units responding to reports of 20 victim shooting incident in 1300 block of S. Waterman. SBPD is working to clear the scene.
— San Bernardino Fire (@SBCityFire)December 2, 2015
A spokeswoman from nearby Loma Linda Medical Center said the hospital was expecting patients momentarily."We're all kind of on standby right now – it could be any minute," spokeswoman Briana Pastorino told Reuters.Here is a map of the area.Hard Closure at Orange Show Rd/ Waterman and Park Center Circle in San Bernardino. AVOID THE AREA POLICE ACTIVITY!
— SB County Sheriff (@sbcountysheriff)December 2, 2015
This is a breaking news story and new information will be added as it becomes available. Please refresh this page for more updates.ACTIVE SHOOTER:Area of Orange Show Rd/ Waterman Ave near Park Center, & surrounding area remains VERY ACTIVE. AVOID! — SB County Sheriff (@sbcountysheriff)December 2, 2015