Syrian Observatory for Human Rights
Syrian rebels cut the main supply route to the part of the city held by the regime, and Assad's army is fighting back hard.
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The messages came as the Syrian government has cut off rebel-held Aleppo from the outside world, potentially trapping the 250,000 people who live there in a violent siege without food, medicine, and other staples.
Human rights groups say US-led coalition airstrikes killed at least 56 civilians in and around the besieged city of Manbij in northern Syria on Monday and Tuesday.
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State television showed debris, mangled cars and wrecked shops in a main commercial thoroughfare near the Sayeda Zeinab shrine in a Damascus suburb.
The London-based Syrian Observatory for Human Rights said Russian warplanes targeted civilian areas around the city's national hospital and other neighborhoods held by a coalition of hardline Islamist rebel groups.
The Syrian Observatory for Human Rights says it arrived at the number by adding up death tolls provided by sources in several Syrian jails and security agencies.
Fighters also reportedly seized control of a checkpoint, a fire station, and university accommodation in Deir al-Zor, not far from Syria's eastern border with Iraq.