The 69-year-old has mild symptoms but has handed over duties to his deputy president for a week. It hasn't been disclosed whether Ramaphosa is carrying the Omicron variant.
Police are also enforcing the strict lockdown using rubber bullets and water cannons.
FBI taking heat over tip about school shooting, two arrested after alleged bomb plot thwarted in NYC, norovirus hits athletes at Winter Olympics, and more.
It's his first day in the job, and he's greeted by a divided party, rampant corruption and a city about to run out of water
Jacob Zuma was pushed out over corruption allegations.
The ANC could move to impeach the 75-year-old within days.